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PTSW0 Dissolution
Cell for Suppositories, Soft Gels, and similar products
Rotary Dialysis Cell for the Testing of Dissolution
Rate of Active Materials in Suppositories and other Lipophilic Samples.
This test accessory can be used in every one of the
Pharma Test dissolution testers except the PTDT 7, as this i sa
"lowhead" design. This diffusion cell is described in the
Japanese Pharmacopoeia. Place the test sample in the cell and seal it off
using the tool provided. Now inject approx. 5ml of the dissolution medium
into the cell and place it into the main cell housing. Immerse the whole
cell into the standard 1 litre vessel which should contoin the dissolution
medium at 37°C. The active material will diffuse out through the membrane
and into the medium, leaving the bulking agents, wax or cocoa butter,
behind. It con now be sampled through the sampling tube provided and
analysed for active content. |